Reduction of number of cases for vaccine-preventable diseases in the United States before and after the introduction of the vaccine – Roush and Murphy (2007)1
| Disease | Number of Annual Prevaccine Cases | Number of Annual Postvaccine Cases | Reduction of Cases after Vaccine Introduction (in %) |
|---|---|---|---|
| Diphteria | 21,053 | 0 | 100% |
| Measles | 530,162 | 55 | 99.90% |
| Mumps | 162,344 | 6,584 | 95.90% |
| Pertussis | 200,752 | 15,632 | 92.20% |
| Poliomyeltis, acute | 19,794 | 0 | 100% |
| Poliomyeltis, paralytic | 16,316 | 0 | 100% |
| Rubella | 47,745 | 11 | 99.90% |
| Congenital rubella syndrome | 152 | 1 | 99.30% |
| Smallpox | 29,005 | 0 | 100% |
| Tetanus | 580 | 41 | 92.90% |
| Hepatitis A | 117,333 | 15,298 | 87% |
| Acute hepatitis B | 66,232 | 13,169 | 80.10% |
| Invasive (Haemophilus influenza type b) | 20,000 | <50 | >99.8% |
| Invasive (pneumococcal disease) | 63,067 | 41,550 | 34.10% |
| Varicella | 4,085,120 | 612,768 | 85 |
Reduction of number of deaths for vaccine-preventable diseases in the United States before and after the introduction of the vaccine – Roush and Murphy (2007)2
| Disease | Number of Annual Prevaccine Deaths | Number of Annual Postvaccine Deaths | Reduction of Deaths after Vaccine Introduction (in %) |
|---|---|---|---|
| Diphteria | 1822 | 0 | 100% |
| Measles | 440 | 0 | 100% |
| Mumps | 39 | 0 | 100% |
| Pertussis | 4034 | 27 | 99.30% |
| Poliomyeltis, acute | 1393 | 0 | 100% |
| Poliomyeltis, paralytic | 1879 | 0 | 100% |
| Rubella | 17 | 0 | 100% |
| Congenital rubella syndrome | -- | 0 | -- |
| Smallpox | 337 | 0 | 100% |
| Tetanus | 472 | 4 | 99.20% |
| Hepatitis A | 137 | 18 | 86.90% |
| Acute hepatitis B | 237 | 47 | 80.20% |
| Invasive (Haemophilus influenza type b) | – | <5 | >99.5 |
| Invasive (pneumococcal disease) | 6500 | 4850 | 25.4 |
| Varicella | 105 | 19 | 81.9 |